Tetrahedron letters

Transition metal promoted synthesis of N, N-dimethyl tertiary amides from 1, 3-dienes

J Szymoniak, D Felix, C Moïse

Index: Szymoniak, Jan; Felix, Didier; Moise, Claude Tetrahedron Letters, 1996 , vol. 37, # 1 p. 33 - 36

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Citation Number: 8

Abstract

A new procedure for a direct conversion of 1, 3-dienes into N, N-dimethyl insaturated tertiary amides is reported. η3-Allyltitanium (III) complexes generated in situ from various dienes reacted regiospecifically with dimethylcarbamoyl chloride to afford products in good to moderate yields. Acyclic, cyclic, incorporated into the polyene systems, and even sterically demanding dienes can be employed.