Tetrahedron

A convenient titanium-mediated intermolecular alkyne–carbonate coupling reaction

A Wolan, F Cadoret, Y Six

Index: Wolan, Andrzej; Cadoret, Frederic; Six, Yvan Tetrahedron, 2009 , vol. 65, # 36 p. 7429 - 7439

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Citation Number: 6

Abstract

A direct diastereoselective titanium-mediated intermolecular coupling of internal alkynes with dialkyl carbonates under Kulinkovich-type reaction conditions is presented. The influence of the structures of the coupling partners on the yields and regioselectivities of this transformation is described.

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