Unsaturated fatty alcohol derivatives of olive oil phenolic compounds with potential low-density lipoprotein (LDL) antioxidant and antiobesity properties

…, M Macias-González, MR Cuevas, M Fitó…

Index: Cotrim, Bruno Almeida; Joglar, Jesus; Rojas, M. Jesus L.; Del Olmo, Juan Manuel Decara; MacIas-Gonzalez, Manuel; Cuevas, Miguel Romero; Fito, Montserrat; Munoz-Aguayo, Daniel; Covas Planells, Maria Isabel; Farre, Magi; Rodriguez De Fonseca, Fernando; De La Torre, Rafael Journal of Agricultural and Food Chemistry, 2012 , vol. 60, # 4 p. 1067 - 1074

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Citation Number: 6

Abstract

A new route for the synthesis of fatty alcohol derivatives of hydroxytyrosol and other olive oil phenolic compounds was developed to allow the preparation of unsaturated derivatives. The biological activity of synthesized compounds was evaluated. Most of the compounds presented a significant antioxidant activity on low-density lipoprotein (LDL) particles. The activity of the tested products was significantly influenced by the number and position of ...