Synthetic Communications®

Synthesis of α, β-Unsaturated Amide via Phosphonium Ylide

S Jiang, K Yang, X Yu

Index: Jiang, Shilei; Yang, Kefeng; Yu, Xiaochun Synthetic Communications, 2009 , vol. 39, # 10 p. 1759 - 1767

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Citation Number: 4

Abstract

The formation of a carbon–carbon double bond is one of the useful and fundamental reactions in synthetic organic chemistry, particularly in the synthesis of complex natural products with biological activity. α,β-Unsaturated amides have been used as building blocks in organic synthesis [ 1-3 View all references ] to prepare natural products. [ 4 4. Takai , K. ; Tezuka , M. ; Utimoto , K. Stereoselective synthesis of trisubstituted α,β-unsaturated esters and amides via reactions of tantalum- ...