Chromium (II)-mediated stereodivergent additions of allylic phosphates and halides to aldehydes
…, CE Tucker, C Jubert, P Knochel
Index: Nowotny, Stefan; Tucker, Charles E.; Jubert, Carole; Knochel, Paul Journal of Organic Chemistry, 1995 , vol. 60, # 9 p. 2762 - 2772
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Citation Number: 47
Abstract
The addition of y-disubstituted allylchromium (II1) reagents to aldehydes proceeds in a stereodivergent manner, in contrast to the case of y-monosubstituted allylchromium (II1) species. The method allows the preparation of a variety of homoallylic alcohols bearing a quaternary center of defined relative configuration in the a-position. The preparation of both stereomeric homoallylic alcohols 13 is possible by using either of the two (E)-or (2)-allylic ...