Chemical communications

Novel amine-catalysed hydroalkoxylation reactions of activated alkenes and alkynes

JE Murtagh, SH McCooey, SJ Connon

Index: Murtagh, Julie E.; McCooey, Seamus H.; Connon, Stephen J. Chemical Communications, 2005 , # 2 p. 227 - 229

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Citation Number: 34

Abstract

Substoichiometric loadings of DBU catalyse the efficient 1, 4-addition of alcohols and non- nucleophilic amines such as pyrrole to activated alkenes; the application of this methodology in a one-pot synthesis of a natural product, and as a novel strategy for the synthesis of mono-protected 1, 3-carbonyl compounds is reported.