Isotope effects—III: Hydrogen isotope effects on conformational equilibria derivatives of cyclohexane

KW Baldry, MJT Robinson

Index: Baldry,K.W.; Robinson,M.J.T. Tetrahedron, 1977 , vol. 33, p. 1663 - 1668

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Citation Number: 20

Abstract

Conformational equilibrium isotope effects (in J mol− 1) have been measured for deuteriation of one methyl or methylene group in the trans stereoisomers of 1, 3- dimethylcyclohexane (− 46±10), 2, 6-(− 80±28) and 3, 5-dimethylcyclohexanone (− 40±15), and 3-methyl-(48±3) and 3-hydroxymethyl 1-trifluoromethylcyclohexane (45—49±3 in toluene, acetone or methanol). The observed effects are independent of solvent for the ...