Organic letters

Facile, Efficient, and Diastereoselective Synthesis of Heterohelicene-like Molecules

W Lin, GL Dou, MH Hu, CP Cao, ZB Huang…

Index: Lin, Wei; Dou, Guo-Lan; Hu, Ming-Hua; Cao, Cheng-Pao; Huang, Zhi-Bin; Shi, Da-Qing Organic Letters, 2013 , vol. 15, # 6 p. 1238 - 1241

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Citation Number: 12

Abstract

A concise and efficient route to new and interesting heterohelicene-like molecules has been developed through the one-pot, cascade reductive coupling reaction of o-hydroxydiimines or o-nitrodiimines and triphosgene in the presence of TiCl4/Sm. Purification of the final products only required a single recrystallization leading to high purity. High diastereoselectivity was also achieved, and two structures of the final products were ...