Mild Cobalt??Catalyzed Hydrocyanation of Olefins with Tosyl Cyanide

B Gaspar, EM Carreira

Index: Gaspar, Boris; Carreira, Erick M. Angewandte Chemie - International Edition, 2007 , vol. 46, # 24 p. 4519 - 4522

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Citation Number: 77

Abstract

The diverse transformations in which nitriles participate [1](for example, RCN! RCO2H, RCONH2, RCHO, RCH2NH2, and RCN4, as well as Pinner and Ritter reactions) place them among the most versatile intermediates in organic chemistry. Although the displacement reactions of leaving groups by cyanide constitute the most common access routes to these, direct olefin hydrocyanation is an attractive alternative. In our continuing interest in the ...

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