Synthesis of febrifugine derivatives and development of an effective and safe tetrahydroquinazoline-type antimalarial

H Kikuchi, S Horoiwa, R Kasahara, N Hariguchi…

Index: European Journal of Medicinal Chemistry, , vol. 76, p. 10 - 19

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Citation Number: 16

Abstract

... European Journal of Medicinal Chemistry. ... The potent antimalarial activity of 1 has stimulated medicinal chemists to pursue derivatives of 1, which may provide valuable leads for novel ... amorphous solid; 1 H NMR (400 MHz, CD 3 OD) δ 8.64 (1H, s), 5.02 (1H, d, J = 17.5 Hz), 4.96 ...