Mechanism of hydrolysis of hydroxy thiolesters in the presence of boric acid

T Okuyama, H Nagamatsu, T Fueno

Index: Okuyama, Tadashi; Nagamatsu, Hiroaki; Fueno, Takayuki Journal of Organic Chemistry, 1981 , vol. 46, # 7 p. 1336 - 1342

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Citation Number: 16

Abstract

Results All the reactions were carried out at 30" C in aqueous solution of constant ionic strength of 0.2 M. The rates were determined spectrophotometrically by following the disappearance of the thiolester absorption. Pseudo-firsborder plots were usually linear over four half-lives. The final spectra of reaction mixtures coincide well with those of expected hydrolysis products (acid+ thiol) except for mea where a nucleophile-like hydrazine was At ...