Tetrahedron

Synthesis of 4, 4-disubstituted cyclohexenones: Part 1. Baeyer-Villiger fragmentation of 1-methoxybicyclo [2.2. 2] oct. 5-enones

AB Holmes, NC Madge

Index: Holmes, Andrew B.; Madge, Nigel C. Tetrahedron, 1989 , vol. 45, # 3 p. 789 - 802

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Citation Number: 9

Abstract

The sodium acetate-buffered peracetic acid oxidation of various 1-methoxybicyclo [2.2. 2] oct- 5-enones (4a-f), and (14), prepared by hydrolysis of the adducts (3)[(13)] derived from dihydroanisole derivatives (2)[(12)] and 2-chloroacrylonitrile leads to 4-substituted cyclohex- 2-en-1-one 4-acetic acid derivatives (7)[(15)].