The reaction of 2??indolecarbohydrazones with ethoxycarbonyl chloride. New synthesis of 2, 3??dihydro??2??oxo??1, 3, 4??oxadiazoles and 1, 2, 3, 4??tetrahydro??4??oxo??5H …

…, P Tabar, E Fernández??Alvarez

Index: Monge, A.; Palop, J. A.; Tabar, P.; Fernandez-Alvarez, E. Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 397 - 400

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Citation Number: 4

Abstract

Abstract The synthesis of 2, 3-dihydro-2-oxo-1, 3, 4-oxadiazole (4) and 5H-pyridazino [4, 5- b] indole (7), are described. Compounds 4 were obtained by reduction of O- ethoxycarbonylcarbohydrazones 3 with sodium borohydride. Compounds 7 were obtained by cyclization of compounds with ethanol/hydrochloric acid and removing the ethoxycarbonyl group with hydrazine. Compounds 3 were obtained by reaction of 2- ...