Aryl Halide Tolerated Electrophilic Amination of Arylboronic Acids with N??Chloroamides Catalyzed by CuCl at Room Temperature

C He, C Chen, J Cheng, C Liu, W Liu…

Index: He, Chuan; Chen, Chong; Cheng, Jin; Liu, Chao; Liu, Wei; Li, Qiang; Lei, Aiwen Angewandte Chemie - International Edition, 2008 , vol. 47, # 34 p. 6414 - 6417

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Citation Number: 89

Abstract

Transition-metal-catalyzed aryl Csp2ÀN bond formation has been intensively studied over the past decade because of the importance of the amines and their derivatives in chemistry related fields.[1–9] The Pd-or Cu-catalyzed formation of anilines from electrophilic aryl halides and nucleophilic primary or secondary amines, pioneered by Buchwald and co- workers and Louie and Hartwig, as well as others,[10–14] is a hallmark reaction in this ...

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