Tetrahedron

Novel reactions of indium reagents with 1, 2-diones: a facile synthesis of α-hydroxy ketones

V Nair, CN Jayan, S Ros

Index: Nair, Vijay; Jayan; Ros, Sindu Tetrahedron, 2001 , vol. 57, # 46 p. 9453 - 9459

Full Text: HTML

Citation Number: 50

Abstract

The advent of Barbier 1 and Grignard reactions heralded a new era in organic chemistry. Although generally ignored for a long time, there has been considerable interest in the Barbier reaction vis a vis other organometallic reactions for the formation of carbon–carbon bonds. Recently, indium mediated Barbier reaction of a variety of functional groups such as aldehydes, ketones, anhydrides, acid chlorides, imides, activated alkenes, alkynes, cyclopropenes, ...