On the mechanism of the palladium-catalyzed tert-butylhydroperoxide-mediated wacker-type oxidation of alkenes using quinoline-2-oxazoline ligands

BW Michel, LD Steffens, MS Sigman

Index: Michel, Brian W.; Steffens, Laura D.; Sigman, Matthew S. Journal of the American Chemical Society, 2011 , vol. 133, # 21 p. 8317 - 8325

Full Text: HTML

Citation Number: 54

Abstract

The mechanism of the tert-butylhydroperoxide-mediated, Pd (Quinox)-catalyzed Wacker- type oxidation was investigated to evaluate the hypothesis that a selective catalyst- controlled oxidation could be achieved by rendering the palladium coordinatively saturated using a bidentate amine ligand. The unique role of the Quinox ligand framework was probed via systematic ligand modifications. The modified ligands were evaluated through ...