Origin of the dendritic effect in multivalent enzyme-like catalysts

G Zaupa, P Scrimin, LJ Prins

Index: Zaupa, Giovanni; Scrimin, Paolo; Prins, Leonard J. Journal of the American Chemical Society, 2008 , vol. 130, # 17 p. 5699 - 5709

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Citation Number: 38

Abstract

Functionalization of multivalent structures such as dendrimers and monolayer passivated nanoparticles with catalytically active groups results in very potent catalysts, a phenomenon described as the positive dendritic effect. Here, we describe a series of peptide dendrons and dendrimers of increasing generation functionalized at the periphery with triazacyclononane, a ligand able to form a strong complex with ZnII. Kinetic studies show ...