. alpha.,. alpha.-Difluoro. beta.-Lactones and Their Thermal Decarboxylation to 1, 1-Difluoroalkenes

…, R Ocampo, R Paredes

Index: Dolbier, William R.; Ocampo, Rogelio; Paredes, Rodrigo Journal of Organic Chemistry, 1995 , vol. 60, # 17 p. 5378 - 5379

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Citation Number: 21

Abstract

@-Lactones have been known for more than 100 years,'and they are readily prepared by a number of methods, 2 perhaps the most generally useful being Adam's method of cyclization of@-hydroxy acids via treatment with benzenesulfonyl chloride in~ yridine.~ This method, and others, have been used to prepare@-lactones of widely diverse structural typesn2 However, to our knowledge, there has been but one mention of a@-lactone which bears ...