Synthetic communications

Odorless thioacetalization reagent 2??[1, 3] dithian??2??ylidene??3??oxo??butanamide and its chemoselectivity

J Liu, Q Liu, H Yu, Y Ouyang, D Dong

Index: Liu, Jun; Liu, Qun; Yu, Haifeng; Ouyang, Yan; Dong, Dewen Synthetic Communications, 2004 , vol. 34, # 24 p. 4545 - 4556

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Citation Number: 16

Abstract

Abstract 2??[1, 3] Dithian/dithiolan??2??ylidene??3??oxo??butanamide 2a/2b were synthesized and investigated in the thioacetalization reaction of aldehydes/ketones 3. The experiments revealed that 2a could be used as a nonthiolic, odorless 1, 3??propanedithiol equivalent in the conversion of aldehydes/ketones into the corresponding dithianes 4, however, 2b was less effective. Moreover, the chemoselectivity of the thioacetalization of 3 in the presence ...