Synthesis of methyl 5 (6)-(4-aminophenoxy)-and 5 (6)-(2-aminophenoxy)-2-benzimidazolyl carbamates and their biological properties

…, SL Kuznetsova, TP Vorobyeva, EV Klimakova

Index: Pilyugin; Mikhailyuk; Kosareva; Chikisheva; Kiseleva; Kuznetsova; Vorobyeva; Klimakova Russian Journal of Organic Chemistry, 2003 , vol. 39, # 8 p. 1154 - 1160

Full Text: HTML

Citation Number: 3

Abstract

Abstract A procedure was developed for preparation of methyl 5 (6)-(4-aminophenoxy)-and 5 (6)-(2-aminophenoxy)-2-benzimidazolyl carbamates by reaction of 3, 4, 4-triaminodiphenyl or 3, 4, 2-triaminodiphenyl ethers respectively with methyl cyanocarbamate in water solution in the presence of 7-10 molar excess of acetic acid. The helminthicidal properties, embryotoxicity, and overall toxicity of compounds obtained were estimated.

Related Articles:

N, O??Diarylation of N??Hydroxycarbamates. Rearrangement and Cleavage Reactions of the Intermediate N, O??Diarylhydroxylamines

[Sheradsky,T.; Salemnick,G. Israel Journal of Chemistry, 1972 , vol. 10, p. 857 - 866]

N, O??Diarylation of N??Hydroxycarbamates. Rearrangement and Cleavage Reactions of the Intermediate N, O??Diarylhydroxylamines

[Sheradsky,T.; Salemnick,G. Israel Journal of Chemistry, 1972 , vol. 10, p. 857 - 866]

N, O??Diarylation of N??Hydroxycarbamates. Rearrangement and Cleavage Reactions of the Intermediate N, O??Diarylhydroxylamines

[Sheradsky,T.; Salemnick,G. Israel Journal of Chemistry, 1972 , vol. 10, p. 857 - 866]

Synthesis of 3, 4, 4'-and 2', 3, 4-Triaminodiphenyl Ethers

[Pilyugin; Mikhailyuk; Kiseleva; Kuznetsova; Chikisheva; Kosareva Russian Journal of General Chemistry, 2003 , vol. 73, # 7 p. 1105 - 1109]

Synthesis of 3, 4, 4'-and 2', 3, 4-Triaminodiphenyl Ethers

[Pilyugin; Mikhailyuk; Kiseleva; Kuznetsova; Chikisheva; Kosareva Russian Journal of General Chemistry, 2003 , vol. 73, # 7 p. 1105 - 1109]

More Articles...