Tetrahedron: Asymmetry

Kinetic resolution of heteroaryl β-hydroxy sulfides catalyzed by Humicola lanuginosa lipase

SS Chimni, S Singh, S Kumar, S Mahajan

Index: Chimni, Swapandeep Singh; Singh, Satwinder; Kumar, Subodh; Mahajan, Savita Tetrahedron Asymmetry, 2002 , vol. 13, # 5 p. 511 - 517

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Citation Number: 10

Abstract

Humicola lanuginosa lipase-catalyzed resolution of heteroaryl substituted β-hydroxy sulfides by irreversible transesterification using vinyl acetate as acylating agent is discussed. The ee of the resolved alcohols was determined from the 1H NMR of their corresponding (S)-(+)-O- acetylmandelic acid esters.