Synthetic Communications

Simple synthesis of N-alkoxymethyl derivatives of anilides

W Danikiewicz, R Szmigielski

Index: Danikiewicz; Szmigielski Synthetic Communications, 2001 , vol. 31, # 19 p. 3047 - 3054

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Citation Number: 4

Abstract

In the present paper we would like to report a simple, two step synthesis of N-alkoxymethyl derivatives of acetanilide, formanilide and benzanilide. In the first step N-(methoxymethyl)anilides are prepared from the corresponding anilides by the action of methoxymethyl chloride under Phase Transfer