Tetrahedron

Copper-catalyzed oxidative cyclization of chalcone and benzylic amine leading to 2, 5-diaryl oxazoles via carbon–carbon double bond cleavage

D Liu, J Yu, J Cheng

Index: Liu, Dongfang; Yu, Jintao; Cheng, Jiang Tetrahedron, 2014 , vol. 70, # 6 p. 1149 - 1153

Full Text: HTML

Citation Number: 1

Abstract

Abstract A copper-catalyzed oxidative cyclization of chalcone with benzylic amine is achieved, providing 2, 5-diaryl oxazoles in moderate to good yields. The procedure employs O 2 as a clean oxidant and involves an oxidative cleavage of the C double bond; length as m-dash