Racemase Activity of B. cepacia Lipase Leads to Dual??Function Asymmetric Dynamic Kinetic Resolution of α??Aminonitriles

…, M Sakulsombat, M Svedendahl Humble…

Index: Vongvilai, Pornrapee; Linder, Mats; Sakulsombat, Morakot; Svedendahl Humble, Maria; Berglund, Per; Brinck, Tore; Ramstroem, Olof Angewandte Chemie - International Edition, 2011 , vol. 50, # 29 p. 6592 - 6595

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Citation Number: 28

Abstract

Chirality is certainly one of the most intriguing phenomena in nature. It generally leads to specific activities and properties that differentiate stereoisomers. As a result, there is a high demand for chiral building blocks, and the search for new and efficient methods for the synthesis of enantiomerically pure compounds has been a major area of research in chemistry.[1] Of the many methods developed, the use of biocatalysts remains especially ...