Aerobic Dehydrogenative Heck Reactions of Heterocycles with Styrenes: A Negative Effect of Metallic Co??Oxidants

A Vasseur, D Harakat, J Muzart…

Index: Vasseur, Alexandre; Harakat, Dominique; Muzart, Jacques; Le Bras, Jean Advanced Synthesis and Catalysis, 2013 , vol. 355, # 1 p. 59 - 67

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Citation Number: 13

Abstract

Abstract The aerobic dehydrogenative Heck reaction (DHR) of heterocycles with styrenes was found to be more efficient in the absence of metallic co-oxidants. According to a study of the isotope effect, the C [BOND] H cleavage was the rate-determining step of the catalytic cycle. Electrospray ionization mass spectrometry, subsequent MS/MS, and high-resolution mass spectrometry were used to detect and characterize catalytic intermediates and ...