Antimalarial agents. 8. Ring-substituted bis (4-aminophenyl) sulfones and their precursors

…, AR Engle, RL Whitaker, GH Singhal

Index: Popoff; Engle; Whitaker; Singhal Journal of medicinal chemistry, 1971 , vol. 14, # 12 p. 1166 - 1169

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Citation Number: 17

Abstract

XXVI NHAc NHAc NHAc 1.6 (20)(60) XXVII NHz NHz NHz 0.2 1.8 2.6 XXVIII COzAle NOz NHAc 3.4 5.0 (60) XXIX C02Me NH2 NHAc 0.3 0.5 0.5 xxx COzhle NHI NHz 12.4 (80)(60) E a UP Basu and KR Chandran, J. Indian Chem. SOC., 27, 123 (1950); Chem. Abstr., 45, 8469e (1951). See footnote c of Table I. See footnote e of Table I. See footnote f of Table I. e 407, cures at 320 mgjkg and 407, toxic deaths at 320 and 640 mg/kg. 40% and 207, toxic ...