Biomimetic synthesis and anti-HIV activity of dimeric phloroglucinols

SK Chauthe, SB Bharate, S Sabde, D Mitra…

Index: Chauthe, Siddheshwar K.; Bharate, Sandip B.; Sabde, Sudeep; Mitra, Debashis; Bhutani, Kamlesh K.; Singh, Inder P. Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 5 p. 2029 - 2036

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Citation Number: 21

Abstract

Plants are an important source of a variety of bioactive compounds with different modes of action. Anti-HIV agents from plant sources can be useful in developing novel therapies for inhibiting HIV infection. Based on the reported anti-HIV activity of plant derived phloroglucinols, several new dimeric phloroglucinols were synthesized in the present study by varying substitution on aromatic ring and at methylene bridge. Some of the synthesized ...