Organic letters

Palladium-catalyzed benzylation of heterocyclic aromatic compounds

D Lapointe, K Fagnou

Index: Lapointe, David; Fagnou, Keith Organic Letters, 2009 , vol. 11, # 18 p. 4160 - 4163

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Citation Number: 86

Abstract

Broadly applicable palladium-catalyzed heteroarene benzylation reactions are described with a focus on the most challenging heterocyclic classes under traditional benzylation techniques such as sulfur-containing heterocycles and those bearing functional groups that would be incompatible with reactions requiring Lewis acids and/or strong bases.