Copper??Catalyzed Domino Route to Natural Nostoclides and Analogues: A Total Synthesis of Nostoclides I and II

SI Ngi, J Petrignet, R Duwald, E Hilali…

Index: Ngi, Samuel Inack; Petrignet, Julien; Duwald, Romain; El Hilali, El Mostafa; Abarbri, Mohamed; Duchene, Alain; Thibonnet, Jerome Advanced Synthesis and Catalysis, 2013 , vol. 355, # 14-15 p. 2936 - 2941

Full Text: HTML

Citation Number: 5

Abstract

Abstract: An original and convenient domino route to natural nostoclides I and II has been developed using a two-step sequence consisting of a copper-catalyzed tandem reaction associated with Suzuki crosscoupling. The methodology employed for this total synthesis appeared to be an interesting and sufficiently flexible tool to allow the synthesis of numerous analogues of these nostoclides. Keywords: copper catalysis; domino reactions; ...