Bulletin of the Korean Chemical Society

Facile Access to a Variety of 2, 5-Biaryl-1, 2, 4-triazol-3-ones via Regioselective N-Arylation of Triazolones

JY Park, JH Chae

Index: Park, Jiyeon; Chae, Junghyun Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 8 p. 2143 - 2146

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Citation Number: 1

Abstract

Abstract A selective synthetic method of the 2, 5-biaryltriazolones has been developed via copper-catalyzed N-arylation reaction. Aryltriazolones, which were readily prepared from commercially available compounds, were N-arylated to 2, 5-biaryltriazolones with high regioselectivity. This approach allows for access to a variety of 2, 5-biaryl-1, 2, 4-trizol-3- ones in a simple and practical manner.