Journal of the American Chemical Society

Chromones. V. The Preparation of 2-Methyl-7-hydroxychromone and 2-Methyl-5, 8-dimethoxy-7-hydroxychromone

TA Geissman

Index: Geissman Journal of the American Chemical Society, 1951 , vol. 73, p. 3514

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Citation Number: 16

Abstract

The preparation of 2-methylchromones from polyhydroxyacetophenones by the reaction of ohydroxyacetophenones with acetic anhydride and sodium acetate'is often unsatisfactory because of the formation of 4-methylcoumarin derivatives or of 3-acetyl-2-methyl-chromones which must be deacylated in a separate step. The C-acylation of ohydroxyacetophenone with ethyl acetate and sodium2 is a reaction which does not readily lend itself to extension ...

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