Tetrahedron Letters

A general synthesis of quinolinones and benzothiazine 1, 1-dioxides via ring closing metathesis

J Minville, J Poulin, C Dufresne, CF Sturino

Index: Minville, Joannie; Poulin, Jason; Dufresne, Claude; Sturino, Claudio F. Tetrahedron Letters, 2008 , vol. 49, # 22 p. 3677 - 3681

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Citation Number: 31

Abstract

A general synthesis of quinolinones and benzothiazine 1, 1-dioxides is presented. A series of N-phenylacrylamides and N-phenylethylenesulfonamides were studied for their ability to undergo ring closing methathesis to yield the corresponding quinolinones and benzothiazine 1, 1-dioxides, respectively. The reactions are general in scope and represents a mild method for the preparation of these heterocycles.

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