The Preparation of 6, 7-Disubstituted Quinoxalines1

JH Boyer, RS Buriks, U Toggweiler

Index: Boyer,J.H. et al. Journal of the American Chemical Society, 1960 , vol. 82, p. 2213 - 2215

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Citation Number: 11

Abstract

Reduction of 1, 2-dinitroso-4-nitroso-5-azidobenzene (111) with an insufficient amount of hydrogen iodide produces 1, 2diamino-4-nitro-bazidobenzene (IV), whereas an excess of hydrogen iodide produces 2, 4, 5-triaminonitrobenzene (I). Condensation with 1, 2- dicarbonyl derivatives gives 6-azido-7-nitroquinoxalines (VIII) from IV and 6-amino-7- nitroquinoxalines (VII) from I. Certain 6-chloro-7-nitroquinoxalines are unreactive toward ...