Chemistry of Pseudoureas1

SE Forman, CA Erickson…

Index: Forman,S.E. et al. Journal of Organic Chemistry, 1963 , vol. 28, p. 2653 - 2658

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Citation Number: 11

Abstract

Trisubstituted pseudoureas undergo a novel base-catalyzed transalkylation of the 0-alkyl group, but the reaction fails with di-and tetrasubstituted analogs. When both of the 3- tiubstituents of trisubstituted pseudoureas are secondary groups, the compounds do not transalkylate but are unstable in alkaline medium. Steric factors displace the equilibrium towards formation of the cyanamide. Disubstituted pseudoureas are likewise unstable in ...