The synthesis of homogeneous triglycerides of eicosapentaenoic acid and docosahexaenoic acid by lipase
GG Haraldsson, BÖ Gudmundsson, Ö Almarsson
Index: Haraldsson, Gudmundur G.; Gudmundsson, Birgir Oe.; Almarsson, Oern Tetrahedron, 1995 , vol. 51, # 3 p. 941 - 952
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Citation Number: 104
Abstract
A highly efficient synthesis of homogeneous triglycerides of either pure eicosapentaenoic acid, 1, or docosahexaenoic acid, 2, by an immobilized non-regiospecific yeast lipase from Candida antarctica is described. Two methods were used: Interesterification of tributyrin and direct esterification of glycerol with stoichiometric amount of 99% EPA or DHA as ethyl esters and free fatty acids, respectively. Both processes were performed under vacuum at 65° C ...
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