Tetrahedron: Asymmetry

Asymmetric synthesis of amathamides A and B: novel alkaloids isolated from Amathia wilsoni

MR Osuna, G Aguirre, R Somanathan, E Molins

Index: Ramirez Osuna, Moises; Aguirre, Gerardo; Somanathan, Ratnasamy; Molins, Elias Tetrahedron Asymmetry, 2002 , vol. 13, # 20 p. 2261 - 2266

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Citation Number: 22

Abstract

Syntheses of the amathamides A and B ((2S)-N-[(E and Z)-2 (2, 4-dibromo-5- methoxyphenylethenyl]-1-methyl-2-pyrrolinecarboxamides), new alkaloids isolated from the Tasmanian marine bryozoan Amathia wilsoni, were accomplished by a sequence of reactions starting from 3-hydroxybenzaldehyde.