Flavin activation by intramolecular acid catalysis at N (1) position

…, S Kawanabe, A Kawase, T Yamaguchi…

Index: Shinkai, Seiji; Kawanabe, Sayuri; Kawase, Akito; Yamaguchi, Toshiro; Manabe, Osamu; et al. Bulletin of the Chemical Society of Japan, 1988 , vol. 61, # 6 p. 2095 - 2102

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Citation Number: 8

Abstract

In order to assess the effect of intramolecular acid catalysis on the specific flavin reactivities, 3-methyl-10-(2-hydroxyphenyl) isoalloxazine (1 (2OH)) and 3-methyl-10-(2-hydroxy-1- naphthyl) isoalloxazine (2 (2OH)) were synthesized and the redox properties were compared with those of reference flavins such as 3-methyl-10-(2-methoxyphenyl) isoalloxazine (1 (2OMe)) and 3-methyl-10-(2-methoxy-1-naphthyl) isoalloxazine (2 (2OMe ...