Domino Cu??Catalyzed C N Coupling/Hydroamidation: A Highly Efficient Synthesis of Nitrogen Heterocycles

…, M Rodríguez Rivero, SL Buchwald

Index: Martin, Ruben; Rivero, Marta Rodriguez; Buchwald, Stephen L. Angewandte Chemie - International Edition, 2006 , vol. 45, # 42 p. 7079 - 7082

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Citation Number: 313

Abstract

Heterocyclic compounds are of great chemical and biological significance.[1] In particular, nitrogen-containing heterocycles are structural constituents of many bioactive natural products, medicinally important compounds, and organic materials.[2] Recent strategies for the synthesis of heterocycles based on metal-catalyzed reactions nicely complement the classical synthetic approaches. Among their advantages is that harsh conditions are ...