Chemical communications

Rh (II)-catalysed room temperature aziridination of homoallyl-carbamates

CJ Hayes, PW Beavis, LA Humphries

Index: Hayes, Christopher J.; Beavis, Peter W.; Humphries, Lesley A. Chemical Communications, 2006 , # 43 p. 4501 - 4502

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Citation Number: 19

Abstract

There has been a recent resurgence of interest in transition metal-catalysed amination reactions and it is now possible to effect efficient and highly selective 1,5- or 1,6-CH insertions under mild conditions using carbamate or sulfamate ester precursors respectively. 1 Du Bois' recent total syntheses of tetrodotoxin and manzacidin A 2 serve as excellent illustrations of what can be achieved using this new synthetic tool. Aziridination has also developed at a fast pace, with ...