Base??and Copper??Catalysed Condensation of Primary Activated Nitro Compounds with Enolisable Compounds

E Trogu, L Cecchi, F De Sarlo, L Guideri…

Index: Trogu, Elena; Cecchi, Luca; De Sarlo, Francesco; Guideri, Luca; Ponticelli, Fabio; Machetti, Fabrizio European Journal of Organic Chemistry, 2009 , # 34 p. 5971 - 5978

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Citation Number: 7

Abstract

Abstract Primary nitro compounds have not been employed as nitrile oxide precursors in reactions with active methylene compounds because the reagents commonly used as dehydrating agents also react with these dipolarophiles. However, the Cu II-catalysed cycloaddition/condensation procedure has been shown to be viable with these substrates, leading directly to the expected polyfunctional isoxazoles provided nitro compounds with ...

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