Synthesis and further studies of chemical transformation of the 2??aryl??3??halogenoquinolin??4 (1H)??one derivatives

MJ Mphahlele, MS Nwamadi…

Index: Mphahlele, Malose J.; Nwamadi, Mutshinyalo S.; Mabeta, Peace Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 2 p. 255 - 260

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Citation Number: 21

Abstract

The 2-arylquinolin-4-ones and their quinoline derivatives continue to receive considerable attention in chemistry because of their wide range of pharmacological applications [1-4]. The 2-arylquinolin-4 (1H)-one derivatives, for example, are known to exhibit antibacterial [1] and antitumour properties [2]. On the other hand, the N-substituted 2-arylquinoline derivatives serve as antimalarial agents, immunostimulants and non-nucleoside HIV-1 inhibitors [3, 4] ...