A mild synthesis of vinyl halides and gem-dihalides using triphenyl phosphite-halogen-based reagents

A Spaggiari, D Vaccari, P Davoli…

Index: Spaggiari, Alberto; Vaccari, Daniele; Davoli, Paolo; Torre, Giovanni; Prati, Fabio Journal of Organic Chemistry, 2007 , vol. 72, # 6 p. 2216 - 2219

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Citation Number: 61

Abstract

A new application of (PhO) 3P-halogen-based reagents to the synthesis of vinyl halides and gem-dihalides is described. Vinyl halides were prepared in good to excellent yields from enolizable ketones, whereas aldehydes afforded the corresponding gem-dihalides. The halogenation proceeded smoothly under mild conditions.