Expedient synthesis of cis-and trans-3-aminocyclobutanecarboxylic acids

…, A Tkachenko, OO Grygorenko, IV Komarov

Index: Radchenko, Dmytro S.; Tkachenko, Anton; Grygorenko, Oleksandr O.; Komarov, Igor V. Synthetic Communications, 2011 , vol. 41, # 11 p. 1644 - 1649

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Abstract

Conformationally restricted amino acids have been shown to be efficient scaffolds in modern drug design. [ 1 1. (a) Cativiela , C. ; Ordóñez , M. Recent progress on the stereoselective synthesis of cyclic quaternary α-amino acids . Tetrahedron: Asymmetry 2009 , 20 , 1 – 63 ; (b) Trabocchi , A. ; Scarpi , D. ; Guarna , A. Structural diversity of bicyclic amino acids . Amino Acids 2008 , 34 , 1 – 24 ; (c) Komarov , IV ; Grygorenko , OO ; Turov , AV ; Khilya , VP Conformationally ...