Uses of K2S2O8 in Metal Catalyzed and Metal Free Oxidative Transformations

Sudip Mandal, Tishyasoumya Bera, Gurudutt Dubey, Jaideep Saha, Joydev K. Laha

Index: 10.1021/acscatal.8b00743

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Abstract

Carbon-carbon/carbon-heteroatom bond formation via oxidative transformation presents one of the state-of-the-arts at the frontiers of chemistry. Potassium persulfate (K2S2O8) has emerged as a cost-effective, suitable inorganic oxidant for a wide array of oxidative transformations ranging from laboratory experiments to industrial processes. The current review provides a comprehensive coverage of oxidative transformations aided with K2S2O8 in the presence or absence of a transition metal catalyst, critical assessment of the results, and underlying mechanisms. The organic chemists could find this review as a useful guide for the expedient synthesis of new chemical entities, to formulate new mechanistic manifolds involving sulfate radical anion, or to design novel oxidative transformations. A detailed understanding of the unsolved mechanisms could further enrich the field.