Towards organo-click reactions: development of pharmaceutical ingredients by using direct organocatalytic bio-mimetic reductions

DB Ramachary, GB Reddy

Index: Ramachary, Dhevalapally B.; Reddy, G. Babul Organic and Biomolecular Chemistry, 2006 , vol. 4, # 24 p. 4463 - 4468

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Citation Number: 61

Abstract

Economic and environmentally friendly bio-mimetic one-pot three and four-component Knoevenagel–hydrogenation (K–H), five-component Knoevenagel–hydrogenation– alkylation (K–H–A) and six-component Knoevenagel–hydrogenation–alkylation–Huisgen cycloaddition (K–H–A–HC) reactions of aldehydes, CH-acids, o-phenylenediamine, alkyl halides and azides using proline, proline–metal carbonate and proline–metal carbonate– ...