Chiral softballs: synthesis and molecular recognition properties

JM Rivera, T Martín, J Rebek

Index: Rivera; Martin; Rebek Jr. Journal of the American Chemical Society, 2001 , vol. 123, # 22 p. 5213 - 5220

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Citation Number: 74

Abstract

Studies on the different congeners of the softball were undertaken to explore structural variants for enantioselective encapsulation. Two different spacer elements in the monomeric subunit render the dimeric softball chiral although the monomer itself is achiral. The dimers represent capsules with dissymmetric cavities with volumes ranging from 190 to 390 Å3. The cavities are distorted spheres, and asymmetric guests, such as naturally occurring ...