Australian journal of chemistry

Controllable Synthesis of Pyrazolo [3, 4-b] pyridines or Substituted Malononitrile Derivatives through Multi-Component Reactions in Ionic Liquid

X Zhang, X Li, X Fan, X Wang, J Wang, G Qu

Index: Zhang, Xinying; Li, Xiaoyan; Fan, Xuesen; Wang, Xia; Wang, Jianji; Qu, Guirong Australian Journal of Chemistry, 2009 , vol. 62, # 4 p. 382 - 388

Full Text: HTML

Citation Number: 8

Abstract

Abstract A multi-component reaction of aldehyde, malononitrile, and 5-amino-3-methyl-1- phenylpyrazole was carried out smoothly in [bmim][BF 4] without any added catalyst. Through this reaction, pyrazolo [3, 4-b] pyridines or substituted malononitrile derivatives were obtained conveniently and controllably at different temperatures. The ionic liquid used can be easily recovered and efficiently reused for at least five runs.

Related Articles:

A simple and efficient preparation of pyrazolo [3, 4??b]??pyridine derivatives through an unexpected reaction of cyanothioacetamide under microwave irradiation

[Fan, Xuesen; Wang, Xia; Zhang, Xinying; Li, Xiaoyan; Qu, Guirong Heteroatom Chemistry, 2008 , vol. 19, # 7 p. 694 - 699]

More Articles...