Flow chemistry syntheses of styrenes, unsymmetrical stilbenes and branched aldehydes

…, M O'Brien, S Kasinathan, P Koos, P Tolstoy…

Index: Bourne, Samuel L.; O'Brien, Matthew; Kasinathan, Sivarajan; Koos, Peter; Tolstoy, Paeivi; Hu, Dennis X.; Bates, Roderick W.; Martin, Benjamin; Schenkel, Berthold; Ley, Steven V. ChemCatChem, 2013 , vol. 5, # 1 p. 159 - 172

Full Text: HTML

Citation Number: 29

Abstract

Abstract Two tandem flow chemistry processes have been developed. A single palladium- catalysed Heck reaction with ethylene gas provides an efficient synthesis for functionalised styrenes. Through further elaboration the catalyst becomes multi-functional and performs a second Heck reaction providing a single continuous process for the synthesis of unsymmetrical stilbenes. In addition, the continuous, rhodium-catalysed, hydroformylation ...