Synthesis and evaluation of fluorinated analogues of monoamine reuptake inhibitors
…, J Kaffy, T Milcent, D Bonnet-Delpon
Index: Philippe, Christine; Kaffy, Julia; Milcent, Thierry; Bonnet-Delpon, Danile Journal of Fluorine Chemistry, 2012 , vol. 134, p. 136 - 145
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Citation Number: 2
Abstract
The synthesis of two series of fluorinated analogues of monoamines reuptake inhibitors based on tertiary alcohols 2-substituted morpholines scaffold has been achieved through the incorporation of fluorinated substituent into 2-substituted morpholino ketones. Their binding affinities have been measured on different monoamine transporters.
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