Helvetica chimica acta

Graphite/Methanesulfonic Acid (GMA) as a New Reagent for Sulfonylation of Phenols and Thia??Fries Rearrangement of Aryl Sulfonates to Sulfonylphenols

H Sharghi, Z Shahsavari??Fard

Index: Sharghi, Hashem; Shahsavari-Fard, Zahra Helvetica Chimica Acta, 2005 , vol. 88, # 1 p. 42 - 52

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Citation Number: 10

Abstract

Abstract A new facile method for direct sulfonylation of phenols was developed. Graphite in methanesulfonic acid (GMA) was used to prepare sulfonylphenols by sulfonylation of phenol and naphthalene derivatives with p-toluenesulfonic acid (= 4-methylbenzenesulfonic acid)(Table 1) and the thia-Fries rearrangement of aryl sulfonates (Table 4). Mechanistic studies showed that the sulfonylation reaction of phenols in GMA occurred through an ...